Switching from cut point A to cut point B in a diabetes screening study will most likely increase which of the following?

In the context of a diabetes screening study, moving from cut point A to cut point B typically involves adjusting the threshold used to determine a positive screening result. When the cut point is lowered to enhance the diagnosis of diabetes, it allows more individuals to be classified as positive for diabetes, which could include those who may not have the condition (thus, introducing more false positives).

The correct answer, which relates to an increase in false negatives, corresponds to the fact that by adopting a lower cut point (cut point B), the sensitivity of the test may improve, allowing more true cases to be detected. However, this does not lead to an increase in false negatives; rather, one could expect a decrease in false negatives as you're capturing more true cases.

Conversely, the increase in false negatives is plausible if cut point B is too low, thus failing to identify some individuals who actually have diabetes. In medical screening terms, a higher sensitivity typically means fewer false negatives. Therefore, the assessment leads to the conclusion that lowering the cut point can unintentionally misclassify individuals who should be recognized as positive.

Such a change could modify the balance of sensitivity and specificity, depending on how the cut points are designated relative to the population's actual diabetes status. The adjustment